PrimePCR™ Probe Assay: EIF6, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0040363
Assay Design:   exonic
Chromosome Location:   20:33872184-33872284question
Amplicon Length:   71
Splice Variants Targeted:   ENST00000374436 ENST00000374443 ENST00000374450 ENST00000456600

Gene Information

Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4) a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein which is insoluble and found both in the nucleus and in the cytoplasm can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   EIF6
Gene Name:   eukaryotic translation initiation factor 6
Aliases:   CAB, EIF3A, ITGB4BP, b(2)gcn, eIF-6, p27(BBP), p27BBP
RefSeq:   NC_000020.10 NG_023238.1 NT_011362.10
Ensembl:   ENSG00000242372
Entrez:   3692
Chromosome Mapping:   20q12

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