PrimePCR™ Probe Assay: TNFRSF8, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: TNFRSF8, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: TNFRSF8, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0040401
Assay Design:   exonic
Chromosome Location:   1:12202902-12203020question
Amplicon Length:   89
Splice Variants Targeted:   ENST00000263932 ENST00000413146 ENST00000417814

Gene Information

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated but not by resting T and B cells. TRAF2 and TRAF5 can interact with this receptor and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq Jul 2008]

Gene Symbol:   TNFRSF8
Gene Name:   tumor necrosis factor receptor superfamily, member 8
Aliases:   CD30, D1S166E, Ki-1
RefSeq:   NC_000001.10 NT_021937.19
Ensembl:   ENSG00000120949
Entrez:   943
Chromosome Mapping:   1p36

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