PrimePCR™ Probe Assay: TYR, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: TYR, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: TYR, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0049664
Assay Design:   exonic
Chromosome Location:   11:88911066-88911209question
Amplicon Length:   114
Splice Variants Targeted:   ENST00000263321

Gene Information

The enzyme encoded by this gene catalyzes the first 2 steps and at least 1 subsequent step in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities and requires copper for function. Mutations in this gene result in oculocutaneous albinism and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. [provided by RefSeq Oct 2008]

Gene Symbol:   TYR
Gene Name:   tyrosinase (oculocutaneous albinism IA)
Aliases:   CMM8, OCA1A, OCAIA, SHEP3
RefSeq:   NC_000011.9 NG_008748.1 NT_167190.1
Ensembl:   ENSG00000077498
Entrez:   7299
Chromosome Mapping:   11q14-q21

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