PrimePCR™ Probe Assay: MET, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: MET, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: MET, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0050378
Assay Design:   exonic
Chromosome Location:   7:116339439-116339546question
Amplicon Length:   78
Splice Variants Targeted:   ENST00000456159 ENST00000397752 ENST00000318493 ENST00000436117

Gene Information

The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   MET
Gene Name:   met proto-oncogene (hepatocyte growth factor receptor)
Aliases:   AUTS9, HGFR, RCCP2, c-Met
RefSeq:   NC_000007.13 NT_007933.15 NG_008996.1
Ensembl:   ENSG00000105976
Entrez:   4233
Chromosome Mapping:   7q31

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