PrimePCR™ Probe Assay: SOS1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: SOS1, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: SOS1, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0050910
Assay Design:   exonic
Chromosome Location:   2:39283881-39284007question
Amplicon Length:   97
Splice Variants Targeted:   ENST00000426016 ENST00000395038 ENST00000451331 ENST00000402219 ENST00000428721

Gene Information

This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq Jul 2008]

Gene Symbol:   SOS1
Gene Name:   son of sevenless homolog 1 (Drosophila)
Aliases:   GF1, GGF1, GINGF, HGF, NS4
RefSeq:   NC_000002.11 NG_007530.1 NT_022184.15
Ensembl:   ENSG00000115904
Entrez:   6654
Chromosome Mapping:   2p21

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