PrimePCR™ Probe Assay: FLNB, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: FLNB, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: FLNB, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0051925
Assay Design:   exonic
Chromosome Location:   3:58135614-58135843question
Amplicon Length:   98
Splice Variants Targeted:   ENST00000490882 ENST00000295956 ENST00000358537 ENST00000429972 ENST00000493452 ENST00000466455 ENST00000348383 ENST00000357272 ENST00000419752

Gene Information

This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3; boomerang dysplasia; autosomal dominant Larsen syndrome; and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq Nov 2009]

Gene Symbol:   FLNB
Gene Name:   filamin B, beta
Aliases:   ABP-278, ABP-280, AOI, DKFZp686A1668, DKFZp686O033, FH1, FLN1L, LRS1, SCT, TABP, TAP
RefSeq:   NC_000003.11 NT_022517.18 NG_012801.1
Ensembl:   ENSG00000136068
Entrez:   2317
Chromosome Mapping:   3p14.3

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