PrimePCR™ Probe Assay: HMGB2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: HMGB2, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: HMGB2, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0053434
Assay Design:   exonic
Chromosome Location:   4:174254739-174255434question
Amplicon Length:   64
Splice Variants Targeted:   ENST00000296503 ENST00000438704 ENST00000446922 ENST00000506267

Gene Information

This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination. [provided by RefSeq Jul 2008]

Gene Symbol:   HMGB2
Gene Name:   high mobility group box 2
Aliases:   HMG2
RefSeq:   NC_000004.11 NT_016354.19
Ensembl:   ENSG00000164104
Entrez:   3148
Chromosome Mapping:   4q31

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