PrimePCR™ Probe Assay: CRADD, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: CRADD, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: CRADD, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0053890
Assay Design:   exonic
Chromosome Location:   12:94072648-94072750question
Amplicon Length:   73
Splice Variants Targeted:   ENST00000552983 ENST00000332896 ENST00000552033 ENST00000548483 ENST00000542893 ENST00000541813

Gene Information

The protein encoded by this gene is a death domain (CARD/DD)-containing protein and has been shown to induce cell apoptosis. Through its CARD domain this protein interacts with and thus recruits caspase 2/ICH1 to the cell death signal transduction complex that includes tumor necrosis factor receptor 1 (TNFR1A) RIPK1/RIP kinase and numbers of other CARD domain-containing proteins. [provided by RefSeq Jul 2008]

Gene Symbol:   CRADD
Gene Name:   CASP2 and RIPK1 domain containing adaptor with death domain
Aliases:   MGC9163, RAIDD
RefSeq:   NC_000012.11 NT_029419.12
Ensembl:   ENSG00000169372
Entrez:   8738
Chromosome Mapping:   12q21.33-q23.1

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