PrimePCR™ Probe Assay: PDZK1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: PDZK1, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: PDZK1, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0054331
Assay Design:   exonic
Chromosome Location:   1:145747104-145747253question
Amplicon Length:   120
Splice Variants Targeted:   ENST00000443667 ENST00000344770 ENST00000417171 ENST00000451928 ENST00000581121 ENST00000583035 ENST00000582332 ENST00000582503

Gene Information

This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq Jan 2011]

Gene Symbol:   PDZK1
Gene Name:   PDZ domain containing 1
Aliases:   CAP70, CLAMP, NHERF-3, NHERF3, PDZD1
RefSeq:   NC_000001.10 NT_167185.1
Ensembl:   ENSG00000174827
Entrez:   5174
Chromosome Mapping:   1q21

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