PrimePCR™ Probe Assay: RPS6KA3, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: RPS6KA3, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: RPS6KA3, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0054492
Assay Design:   exonic
Chromosome Location:   X:20222207-20227496question
Amplicon Length:   76
Splice Variants Targeted:   ENST00000379565 ENST00000457145 ENST00000438357 ENST00000544447 ENST00000540702 ENST00000379548

Gene Information

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS). [provided by RefSeq Jul 2008]

Gene Symbol:   RPS6KA3
Gene Name:   ribosomal protein S6 kinase, 90kDa, polypeptide 3
Aliases:   CLS, HU-3, ISPK-1, MAPKAPK1B, MRX19, RSK, RSK2, S6K-alpha3, p90-RSK2, pp90RSK2
RefSeq:   NC_000023.10 NG_007488.1 NT_167197.1
Ensembl:   ENSG00000177189
Entrez:   6197
Chromosome Mapping:   Xp22.2-p22.1

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