PrimePCR™ Probe Assay: TGM2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0055668
Assay Design:   exonic
Chromosome Location:   20:36789890-36793599question
Amplicon Length:   91
Splice Variants Targeted:   ENST00000361475 ENST00000373403 ENST00000453095 ENST00000536701 ENST00000358775 ENST00000359373 ENST00000393605 ENST00000334211 ENST00000393609 ENST00000426523 ENST00000429686 ENST00000455638

Gene Information

Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer is induced by retinoic acid and appears to be involved in apoptosis. Finally the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   TGM2
Gene Name:   transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
Aliases:   G-ALPHA-h, GNAH, TG2, TGC
RefSeq:   NC_000020.10 NT_011362.10
Ensembl:   ENSG00000198959
Entrez:   7052
Chromosome Mapping:   20q12

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