PrimePCR™ Probe Assay: PIK3CB, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: PIK3CB, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: PIK3CB, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0057745
Assay Design:   exonic
Chromosome Location:   3:138413744-138417886question
Amplicon Length:   114
Splice Variants Targeted:   ENST00000477593 ENST00000493568 ENST00000289153 ENST00000544716

Gene Information

This gene encodes an isoform of the catalytic subunit of phosphoinositide 3-kinase (PI3K). These kinases are important in signaling pathways involving receptors on the outer membrane of eukaryotic cells and are named for their catalytic subunit. The encoded protein is the catalytic subunit for PI3Kbeta (PI3KB). PI3KB has been shown to be part of the activation pathway in neutrophils which have bound immune complexes at sites of injury or infection. Alternative splicing results in multiple transcript variants. [provided by RefSeq Dec 2011]

Gene Symbol:   PIK3CB
Gene Name:   phosphoinositide-3-kinase, catalytic, beta polypeptide
Aliases:   DKFZp779K1237, MGC133043, P110BETA, PI3K, PI3KBETA, PIK3C1
RefSeq:   NC_000003.11 NT_005612.16
Ensembl:   ENSG00000051382
Entrez:   5291
Chromosome Mapping:   3q22.3

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