PrimePCR™ Probe Assay: BMP6, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: BMP6, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: BMP6, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0031092
Assay Design:   Intron-spanning
Chromosome Location:   6:7845454-7861741question
Amplicon Length:   140
Splice Variants Targeted:   ENST00000283147 ENST00000540959 ENST00000537240

Gene Information

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis the BMP encoded by this gene has a proposed role in early development. In addition the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity. [provided by RefSeq Jul 2008]

Gene Symbol:   BMP6
Gene Name:   bone morphogenetic protein 6
Aliases:   VGR, VGR1
RefSeq:   NC_000006.11 NT_007592.15
Ensembl:   ENSG00000153162
Entrez:   654
Chromosome Mapping:   6p24-p23

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