PrimePCR™ Probe Assay: ATF2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0040492
Assay Design:   Intron-spanning
Chromosome Location:   2:175979570-175982795question
Amplicon Length:   75
Splice Variants Targeted:   ENST00000264110 ENST00000345739 ENST00000409635 ENST00000435004 ENST00000392544 ENST00000437522 ENST00000409833 ENST00000426833 ENST00000538946 ENST00000487334

Gene Information

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE) an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq Jan 2012]

Gene Symbol:   ATF2
Gene Name:   activating transcription factor 2
Aliases:   CRE-BP1, CREB2, HB16, MGC111558, TREB7
RefSeq:   NC_000002.11 NT_005403.17
Ensembl:   ENSG00000115966
Entrez:   1386
Chromosome Mapping:   2q32

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