PrimePCR™ lncRNA® Probe Assay:PSME2, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression.

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   Same primer pair as used in SYBR assay qhsaLED0214482

List Price:    $247.00
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PrimePCR™ IncRNA PreAmp for Probe Assay: PSME2, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ IncRNA Template for Probe Assay: PSME2, Human
Reaction:     4 billion copies/200 µl
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   lncRNA Expression
Unique Assay ID:   qhsaLEP0215918
Assay Design:   exonic
Chromosome Location:   chr14:24143736-24143872question
Amplicon Length:   107
Splice Variants Targeted:   ENST00000471700 ENST00000560410 ENST00000615264 ENST00000558931 ENST00000558273 ENST00000216802 ENST00000560370 ENST00000559005 ENST00000559042 ENST00000559453
LNCipedia Splice Variants Targeted:   lnc-PSME2-1:2 lnc-PSME2-1:1

Gene Information

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base which contains 6 ATPase subunits and 2 non-ATPase subunits and a lid which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome the immunoproteasome is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator referred to as the 11S regulator or PA28 that replaces the 19S regulator. Three subunits (alpha beta and gamma) of the 11S regulator have been identified. This gene encodes the beta subunit of the 11S regulator one of the two 11S subunits that is induced by gamma-interferon. Three beta and three alpha subunits combine to form a heterohexameric ring. Six pseudogenes have been identified on chromosomes 4 5 8 10 and 13. [provided by RefSeq Jul 2008]

Gene Symbol:   PSME2
Gene Name:   proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
Aliases:   PA28B, PA28beta, REGbeta
RefSeq:   NC_000014.8 NT_026437.12
Ensembl:   ENSG00000100911
LNCipedia:   lnc-PSME2-1
Entrez:   5721
Chromosome Mapping:   14q11.2
Gene Strand:   Not Available

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