DNA repair-deficiency disorders

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Disease State Panels

PrimePCR disease state panels were designed by referencing the National Library of Medicine database. Disease state panels allow for the thorough investigation of differentially expressed genes within a specified pathology.

Gene targets for each disease state were ranked and compared according to the following criteria:

  • Frequency of gene expression changes in biomarker studies
  • Popularity in overall medical research
  • Popularity in current medical research

The resulting gene scores were used to design real-time PCR panels. For diseases with a large number of gene targets, multiple tiered plates are available. Tier 1 plates represent the highest ranked targets with subsequent tiers containing the lower ranked or less well characterized targets.

Target Details

Click on a target from the pathway image to view related information.