PrimePCR Disease State Panels were designed by referencing the National Library of Medicine database. Disease state panels allow for the thorough investigation of differentially expressed genes within a specified pathology.
Gene targets for each disease state were ranked and compared according to the following criteria:
Frequency of gene expression changes in biomarker studies
Popularity in overall medical research
Popularity in current medical research
The resulting gene scores were used to design real-time PCR panels. For diseases with a large number of gene targets, multiple tiered plates are available. Tier 1 plates represent the highest ranked targets with subsequent tiers containing the lower ranked or less well characterized targets.
Bacterial infections and mycoses