PrimePCR™ Probe Assay: TLR9, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0025865
Assay Design:   Exonic
Chromosome Location:   3:52259820-52259947question
Amplicon Length:   98
Splice Variants Targeted:   ENST00000360658

Gene Information

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues such as spleen lymph node bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response. [provided by RefSeq Jul 2008]

Gene Symbol:   TLR9
Gene Name:   toll-like receptor 9
Aliases:   CD289
RefSeq:   NC_000003.11 NT_022517.18
Ensembl:   ENSG00000239732
Entrez:   54106
Chromosome Mapping:   3p21.3

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