PrimePCR™ Probe Assay: ALDOA, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0040808
Assay Design:   exonic
Chromosome Location:   16:30078888-30079970question
Amplicon Length:   68
Splice Variants Targeted:   ENST00000338110 ENST00000395248 ENST00000566897 ENST00000562168 ENST00000569545 ENST00000563060 ENST00000412304 ENST00000563987 ENST00000564546 ENST00000564595 ENST00000569798 ENST00000395240 ENST00000566846 ENST00000562679 ENST00000564688 ENST00000261254

Gene Information

The protein encoded by this gene Aldolase A (fructose-bisphosphate aldolase) is a glycolytic enzyme that catalyzes the reversible conversion of fructose-16-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A B and C) encoded by three different genes are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing and alternative promoter usage results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 10. [provided by RefSeq Aug 2011]

Gene Symbol:   ALDOA
Gene Name:   aldolase A, fructose-bisphosphate
Aliases:   ALDA, GSD12, MGC10942, MGC17716, MGC17767
RefSeq:   NC_000016.9 NG_008010.1 NT_010393.16
Ensembl:   ENSG00000149925
Entrez:   226
Chromosome Mapping:   16p11.2

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