PrimePCR™ Probe Assay: BIRC3, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0049289
Assay Design:   exonic
Chromosome Location:   11:102195950-102196063question
Amplicon Length:   84
Splice Variants Targeted:   ENST00000263464 ENST00000532808 ENST00000532609 ENST00000527309

Gene Information

This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq Aug 2011]

Gene Symbol:   BIRC3
Gene Name:   baculoviral IAP repeat containing 3
Aliases:   AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2
RefSeq:   NC_000011.9 NT_033899.8
Ensembl:   ENSG00000023445
Entrez:   330
Chromosome Mapping:   11q22

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