PrimePCR™ Probe Assay: FANCL, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0050872
Assay Design:   exonic
Chromosome Location:   2:58392887-58425715question
Amplicon Length:   95
Splice Variants Targeted:   ENST00000540646 ENST00000417361 ENST00000427708 ENST00000446381 ENST00000403676 ENST00000449070 ENST00000233741 ENST00000402135 ENST00000403295

Gene Information

The Fanconi anemia complementation group (FANC) currently includes FANCA FANCB FANCC FANCD1 (also called BRCA2) FANCD2 FANCE FANCF FANCG FANCI FANCJ (also called BRIP1) FANCL FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability hypersensitivity to DNA crosslinking agents increased chromosomal breakage and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group L. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq Jul 2008]

Gene Symbol:   FANCL
Gene Name:   Fanconi anemia, complementation group L
Aliases:   FAAP43, FLJ10335, PHF9, POG
RefSeq:   NC_000002.11 NT_022184.15 NG_007418.1
Ensembl:   ENSG00000115392
Entrez:   55120
Chromosome Mapping:   2p16.1

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