PrimePCR™ Probe Assay: KDR, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0051468
Assay Design:   exonic
Chromosome Location:   4:55945654-55945795question
Amplicon Length:   112
Splice Variants Targeted:   ENST00000263923

Gene Information

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor known as kinase insert domain receptor is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation survival migration tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors including Rab GTPase P2Y purine nucleotide receptor integrin alphaVbeta3 T-cell protein tyrosine phosphatase etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq May 2009]

Gene Symbol:   KDR
Gene Name:   kinase insert domain receptor (a type III receptor tyrosine kinase)
Aliases:   CD309, FLK1, VEGFR, VEGFR2
RefSeq:   NC_000004.11 NG_012004.1 NT_022853.15
Ensembl:   ENSG00000128052
Entrez:   3791
Chromosome Mapping:   4q11-q12

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