PrimePCR™ Probe Assay: TLN1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0052006
Assay Design:   exonic
Chromosome Location:   9:35697755-35697852question
Amplicon Length:   68
Splice Variants Targeted:   ENST00000314888 ENST00000540444

Gene Information

This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin actin and vinculin. [provided by RefSeq Feb 2009]

Gene Symbol:   TLN1
Gene Name:   talin 1
Aliases:   ILWEQ, KIAA1027, TLN
RefSeq:   NC_000009.11 NT_008413.18
Ensembl:   ENSG00000137076
Entrez:   7094
Chromosome Mapping:   9p13

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