PrimePCR™ Probe Assay: SAP18, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0052740
Assay Design:   exonic
Chromosome Location:   13:21721064-21721445question
Amplicon Length:   94
Splice Variants Targeted:   ENST00000382533 ENST00000450573

Gene Information

Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex which includes SIN3 SAP30 HDAC1 HDAC2 RbAp46 RbAp48 and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. A pseudogene has been identified on chromosome 2. [provided by RefSeq Dec 2008]

Gene Symbol:   SAP18
Gene Name:   Sin3A-associated protein, 18kDa
Aliases:   2HOR0202, MGC27131, SAP18P
RefSeq:   NC_000013.10 NT_024524.14
Ensembl:   ENSG00000150459
Entrez:   10284
Chromosome Mapping:   13q12.11

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