PrimePCR™ Probe Assay: MAP3K11, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0054235
Assay Design:   exonic
Chromosome Location:   11:65375761-65375909question
Amplicon Length:   119
Splice Variants Targeted:   ENST00000529839 ENST00000526293 ENST00000530153 ENST00000309100

Gene Information

The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate and activates IkappaB kinase alpha and beta and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42. [provided by RefSeq Jul 2008]

Gene Symbol:   MAP3K11
Gene Name:   mitogen-activated protein kinase kinase kinase 11
Aliases:   MEKK11, MGC17114, MLK-3, MLK3, PTK1, SPRK
RefSeq:   NC_000011.9 NT_167190.1
Ensembl:   ENSG00000173327
Entrez:   4296
Chromosome Mapping:   11q13.1-q13.3

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