PrimePCR™ Probe Assay: XRCC6, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0055342
Assay Design:   exonic
Chromosome Location:   22:42059935-42060037question
Amplicon Length:   73
Splice Variants Targeted:   ENST00000360079 ENST00000402580 ENST00000359308 ENST00000405878 ENST00000405506 ENST00000428575

Gene Information

The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair transposition and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq Jul 2008]

Gene Symbol:   XRCC6
Gene Name:   X-ray repair complementing defective repair in Chinese hamster cells 6
Aliases:   CTC75, CTCBF, G22P1, KU70, ML8, TLAA
RefSeq:   NC_000022.10 NT_011520.12
Ensembl:   ENSG00000196419
Entrez:   2547
Chromosome Mapping:   22q13.2

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