PrimePCR™ Probe Assay: KRT13, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0058438
Assay Design:   exonic
Chromosome Location:   17:39661690-39661835question
Amplicon Length:   116
Splice Variants Targeted:   ENST00000587435 ENST00000587544 ENST00000336861 ENST00000246635

Gene Information

The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. The type I cytokeratins are clustered in a region of chromosome 17q21.2. Alternative splicing of this gene results in multiple transcript variants; however not all variants have been described. [provided by RefSeq Jul 2008]

Gene Symbol:   KRT13
Gene Name:   keratin 13
Aliases:   CK13, K13, MGC161462, MGC3781
RefSeq:   NC_000017.10 NT_010783.15 NG_008406.1
Ensembl:   ENSG00000171401
Entrez:   3860
Chromosome Mapping:   17q12-q21.2

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