PrimePCR™ Probe Assay: IRAK4, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0027198
Assay Design:   Intron-spanning
Chromosome Location:   12:44176212-44180226question
Amplicon Length:   140
Splice Variants Targeted:   ENST00000440781 ENST00000448290 ENST00000551736 ENST00000356669 ENST00000431837

Gene Information

This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Aug 2011]

Gene Symbol:   IRAK4
Gene Name:   interleukin-1 receptor-associated kinase 4
Aliases:   IPD1, NY-REN-64, REN64
RefSeq:   NC_000012.11 NT_029419.12 NG_009892.1
Ensembl:   ENSG00000198001
Entrez:   51135
Chromosome Mapping:   12q12

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