PrimePCR™ Probe Assay: IRS2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0028619
Assay Design:   Intron-spanning
Chromosome Location:   13:110408626-110434464question
Amplicon Length:   76
Splice Variants Targeted:   ENST00000375856

Gene Information

This gene encodes the insulin receptor substrate 2 a cytoplasmic signaling molecule that mediates effects of insulin insulin-like growth factor 1 and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment. [provided by RefSeq Jul 2008]

Gene Symbol:   IRS2
Gene Name:   insulin receptor substrate 2
Aliases:   IRS-2
RefSeq:   NC_000013.10 NG_008154.1 NT_009952.14
Ensembl:   ENSG00000185950
Entrez:   8660
Chromosome Mapping:   13q34

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