PrimePCR™ Probe Assay: CBX5, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0028637
Assay Design:   Intron-spanning
Chromosome Location:   12:54635560-54639938question
Amplicon Length:   140
Splice Variants Targeted:   ENST00000209875 ENST00000439541 ENST00000550489 ENST00000550411

Gene Information

This gene encodes a highly conserved nonhistone protein which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants encoding the same protein have been identified. [provided by RefSeq Jul 2008]

Gene Symbol:   CBX5
Gene Name:   chromobox homolog 5
Aliases:   HP1, HP1A
RefSeq:   NC_000012.11 NT_029419.12
Ensembl:   ENSG00000094916
Entrez:   23468
Chromosome Mapping:   12q13.13

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