PrimePCR™ Probe Assay: GRIN2B, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0029797
Assay Design:   Intron-spanning
Chromosome Location:   12:13717451-13720014question
Amplicon Length:   149
Splice Variants Targeted:   ENST00000279593

Gene Information

N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1) NR2 (GRIN2A GRIN2B GRIN2C or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain. [provided by RefSeq Jul 2008]

Gene Symbol:   GRIN2B
Gene Name:   glutamate receptor, ionotropic, N-methyl D-aspartate 2B
Aliases:   MGC142178, MGC142180, NMDAR2B, NR2B, hNR3
RefSeq:   NC_000012.11 NT_009714.17
Ensembl:   ENSG00000150086
Entrez:   2904
Chromosome Mapping:   12p12

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