PrimePCR™ Probe Assay: TIMP3, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0029799
Assay Design:   Intron-spanning
Chromosome Location:   22:33245484-33253346question
Amplicon Length:   119
Splice Variants Targeted:   ENST00000266085 ENST00000382049 ENST00000538671

Gene Information

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy. [provided by RefSeq Jul 2008]

Gene Symbol:   TIMP3
Gene Name:   TIMP metallopeptidase inhibitor 3
Aliases:   HSMRK222, K222, K222TA2, SFD
RefSeq:   NC_000022.10 NG_009117.1 NT_011520.12
Ensembl:   ENSG00000100234
Entrez:   7078
Chromosome Mapping:   22q12.1-q13.2,22q12.3

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