PrimePCR™ Probe Assay: FGA, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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PrimePCR™ PreAmp for Probe Assay: FGA, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: FGA, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0030820
Assay Design:   Intron-spanning
Chromosome Location:   4:155510608-155511835question
Amplicon Length:   127
Splice Variants Targeted:   ENST00000302053 ENST00000403106 ENST00000457487

Gene Information

The protein encoded by this gene is the alpha component of fibrinogen a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading display vasoconstrictor and chemotactic activities and are mitogens for several cell types. Mutations in this gene lead to several disorders including dysfibrinogenemia hypofibrinogenemia afibrinogenemia and renal amyloidosis. Alternative splicing results in two isoforms which vary in the carboxy-terminus. [provided by RefSeq Jul 2008]

Gene Symbol:   FGA
Gene Name:   fibrinogen alpha chain
Aliases:   Fib2, MGC119422, MGC119423, MGC119425
RefSeq:   NC_000004.11 NG_008832.1 NT_016354.19
Ensembl:   ENSG00000171560
Entrez:   2243
Chromosome Mapping:   4q28

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