PrimePCR™ Probe Assay: FSCN1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0032508
Assay Design:   Intron-spanning
Chromosome Location:   7:5643624-5645005question
Amplicon Length:   111
Splice Variants Targeted:   ENST00000382361 ENST00000340250 ENST00000535097

Gene Information

This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration motility adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq Sep 2011]

Gene Symbol:   FSCN1
Gene Name:   fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
Aliases:   FLJ38511, SNL, p55
RefSeq:   NC_000007.13 NT_007819.17
Ensembl:   ENSG00000075618
Entrez:   6624
Chromosome Mapping:   7p22

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