PrimePCR™ Probe Assay: PTPN22, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0032986
Assay Design:   Intron-spanning
Chromosome Location:   1:114377587-114380347question
Amplicon Length:   135
Splice Variants Targeted:   ENST00000359785 ENST00000528414 ENST00000420377 ENST00000525799 ENST00000538253 ENST00000354605

Gene Information

This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes rheumatoid arthritis systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq Mar 2009]

Gene Symbol:   PTPN22
Gene Name:   protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
Aliases:   LYP, LYP1, LYP2, PEP, PTPN8
RefSeq:   NC_000001.10 NT_032977.9 NG_011432.1
Ensembl:   ENSG00000134242
Entrez:   26191
Chromosome Mapping:   1p13.2

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