PrimePCR™ Probe Assay: PSMA1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0041648
Assay Design:   exonic
Chromosome Location:   11:14535125-14535240question
Amplicon Length:   86
Splice Variants Targeted:   ENST00000419365 ENST00000396394 ENST00000530457 ENST00000418988 ENST00000396393

Gene Information

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome the immunoproteasome is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family that is a 20S core alpha subunit. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq Jan 2009]

Gene Symbol:   PSMA1
Gene Name:   proteasome (prosome, macropain) subunit, alpha type, 1
Aliases:   HC2, MGC14542, MGC14575, MGC14751, MGC1667, MGC21459, MGC22853, MGC23915, NU, PROS30
RefSeq:   NC_000011.9 NT_009237.18
Ensembl:   ENSG00000129084
Entrez:   5682
Chromosome Mapping:   11p15.1

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