PrimePCR™ Probe Assay: NFKBIA, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0050091
Assay Design:   exonic
Chromosome Location:   14:35870801-35870903question
Amplicon Length:   73
Splice Variants Targeted:   ENST00000216797 ENST00000557140 ENST00000557389

Gene Information

This gene encodes a member of the NF-kappa-B inhibitor family which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq Aug 2011]

Gene Symbol:   NFKBIA
Gene Name:   nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
Aliases:   IKBA, MAD-3, NFKBI
RefSeq:   NC_000014.8 NG_007571.1 NT_026437.12
Ensembl:   ENSG00000100906
Entrez:   4792
Chromosome Mapping:   14q13

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