PrimePCR™ Probe Assay: CASP9, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0051738
Assay Design:   exonic
Chromosome Location:   1:15844709-15844812question
Amplicon Length:   74
Splice Variants Targeted:   ENST00000546424 ENST00000333868 ENST00000348549 ENST00000375890 ENST00000447522 ENST00000440484

Gene Information

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits large and small that dimerize to form the active enzyme. This protein is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade. Alternative splicing results in two transcript variants which encode different isoforms. [provided by RefSeq Jul 2008]

Gene Symbol:   CASP9
Gene Name:   caspase 9, apoptosis-related cysteine peptidase
Aliases:   APAF-3, APAF3, CASPASE-9c, ICE-LAP6, MCH6
RefSeq:   NC_000001.10 NT_004610.19
Ensembl:   ENSG00000132906
Entrez:   842
Chromosome Mapping:   1p36.21

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