PrimePCR™ Probe Assay: CTSL1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0051849
Assay Design:   exonic
Chromosome Location:   9:90344503-90344631question
Amplicon Length:   99
Splice Variants Targeted:   ENST00000343150 ENST00000340342

Gene Information

The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin as well as alpha-1 protease inhibitor a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes including myofibril necrosis in myopathies and in myocardial ischemia and in the renal tubular response to proteinuria. This protein which is a member of the peptidase C1 family is a dimer composed of disulfide-linked heavy and light chains both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq Apr 2012]

Gene Symbol:   CTSL1
Gene Name:   cathepsin L1
Aliases:   CATL, CTSL, FLJ31037, MEP
RefSeq:   NC_000009.11 NT_008470.19
Ensembl:   ENSG00000135047
Entrez:   1514
Chromosome Mapping:   9q21.33

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