PrimePCR™ Probe Assay: IL2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0029918
Assay Design:   Intron-spanning
Chromosome Location:   4:123372970-123374938question
Amplicon Length:   92
Splice Variants Targeted:   ENST00000226730

Gene Information

The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq Jul 2008]

Gene Symbol:   IL2
Gene Name:   interleukin 2
Aliases:   IL-2, TCGF, lymphokine
RefSeq:   NC_000004.11 NG_016779.1 NT_016354.19
Ensembl:   ENSG00000109471
Entrez:   3558
Chromosome Mapping:   4q26-q27

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