PrimePCR™ Probe Assay: IL1A, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0030471
Assay Design:   Intron-spanning
Chromosome Location:   2:113532757-113535631question
Amplicon Length:   126
Splice Variants Targeted:   ENST00000263339

Gene Information

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses inflammatory processes and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein which is proteolytically processed and released in response to cell injury and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. [provided by RefSeq Jul 2008]

Gene Symbol:   IL1A
Gene Name:   interleukin 1, alpha
Aliases:   IL-1A, IL1, IL1-ALPHA, IL1F1
RefSeq:   NC_000002.11 NG_008850.1 NT_022135.16
Ensembl:   ENSG00000115008
Entrez:   3552
Chromosome Mapping:   2q14

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