PrimePCR™ Probe Assay: ACVR1B, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0031397
Assay Design:   Intron-spanning
Chromosome Location:   12:52377860-52379017question
Amplicon Length:   103
Splice Variants Targeted:   ENST00000257963 ENST00000541224 ENST00000426655 ENST00000415850 ENST00000542485

Gene Information

This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq Jun 2010]

Gene Symbol:   ACVR1B
Gene Name:   activin A receptor, type IB
Aliases:   ACTRIB, ACVRLK4, ALK4, SKR2
RefSeq:   NC_000012.11 NT_029419.12 NG_022926.1
Ensembl:   ENSG00000135503
Entrez:   91
Chromosome Mapping:   12q13

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