PrimePCR™ Probe Assay: PTGDS, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0032811
Assay Design:   Intron-spanning
Chromosome Location:   9:139874398-139874721question
Amplicon Length:   174
Splice Variants Targeted:   ENST00000371625 ENST00000446677 ENST00000224167

Gene Information

The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep. [provided by RefSeq Jul 2008]

Gene Symbol:   PTGDS
Gene Name:   prostaglandin D2 synthase 21kDa (brain)
Aliases:   L-PGDS, LPGDS, PDS, PGD2, PGDS, PGDS2
RefSeq:   NC_000009.11 NT_024000.16
Ensembl:   ENSG00000107317
Entrez:   5730
Chromosome Mapping:   9q34.2-q34.3

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