PrimePCR™ Probe Assay: BNIP3, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0040441
Assay Design:   Intron-spanning
Chromosome Location:   10:133784372-133786617question
Amplicon Length:   153
Splice Variants Targeted:   ENST00000368636 ENST00000540159

Gene Information

This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19 kDa-like sequences of BCL2 another apoptotic protector. This protein contains a BH3 domain and a transmembrane domain which have been associated with pro-apoptotic function. The dimeric mitochondrial protein encoded by this gene is known to induce apoptosis even in the presence of BCL2. [provided by RefSeq Mar 2011]

Gene Symbol:   BNIP3
Gene Name:   BCL2/adenovirus E1B 19kDa interacting protein 3
Aliases:   NIP3
RefSeq:   NC_000010.10 NT_008818.16
Ensembl:   ENSG00000176171
Entrez:   664
Chromosome Mapping:   10q26.3

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