PrimePCR™ lncRNA® Probe Assay:IL12RB2, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression.

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   Same primer pair as used in SYBR assay qhsaLED0103816

List Price:    $247.00
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PrimePCR™ IncRNA PreAmp for Probe Assay: IL12RB2, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ IncRNA Template for Probe Assay: IL12RB2, Human
Reaction:     4 billion copies/200 µl
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   lncRNA Expression
Unique Assay ID:   qhsaLEP0181056
Assay Design:   exonic
Chromosome Location:   chr1:67396418-67396566question
Amplicon Length:   119
Refseq Transcripts Amplified:   XM_005270825,XM_011541384,XM_006710617,XM_005270827,XM_017001203,XM_005270828,NM_001258214,NM_001319233,NM_001559,NM_001258216,NM_001258215,XM_011541383,NR_047584,NR_047583
Splice Variants Targeted:   ENST00000544434 ENST00000262345 ENST00000541374
LNCipedia Splice Variants Targeted:   lnc-IL12RB2-3:1

Gene Information

The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases such as Crohn's disease and leprosy which is thought to contribute to the inflammatory response and host defense. [provided by RefSeq Jul 2008]

Gene Symbol:   IL12RB2
Gene Name:   interleukin 12 receptor, beta 2
Aliases:   Not Available
RefSeq:   NC_000001.10 NT_032977.9
Ensembl:   ENSG00000081985
LNCipedia:   lnc-IL12RB2-3
Entrez:   3595
Chromosome Mapping:   1p31.3-p31.2
Gene Strand:   Not Available

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