PrimePCR™ lncRNA® Probe Assay:LTB, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression.

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   Same primer pair as used in SYBR assay qhsaLED0104740

List Price:    $247.00
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PrimePCR™ IncRNA PreAmp for Probe Assay: LTB, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ IncRNA Template for Probe Assay: LTB, Human
Reaction:     4 billion copies/200 µl
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   lncRNA Expression
Unique Assay ID:   qhsaLEP0181980
Assay Design:   exonic
Chromosome Location:   chr6:31580844-31580992question
Amplicon Length:   119
Refseq Transcripts Amplified:   NM_009588,NM_002341
Splice Variants Targeted:   ENST00000483972 ENST00000482429 ENST00000429299 ENST00000446745
LNCipedia Splice Variants Targeted:   lnc-NCR3-1:2

Gene Information

Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq Jul 2008]

Gene Symbol:   LTB
Gene Name:   lymphotoxin beta (TNF superfamily, member 3)
Aliases:   TNFC, TNFSF3, p33
RefSeq:   NC_000006.11 NT_007592.15 NT_113891.2 NT_167244.1 NT_167245.1 NT_167246.1 NT_167247.1 NT_167248.1 NT_167249.1
Ensembl:   ENSG00000227507
LNCipedia:   lnc-NCR3-1
Entrez:   4050
Chromosome Mapping:   6p21.3
Gene Strand:   Not Available

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