PrimePCR™ SYBR® Green Assay: ABCC8, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Recommended - best coverage

List Price:    $179.00
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PrimePCR™ PreAmp for SYBR® Green Assay: ABCC8, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for SYBR® Green Assay: ABCC8, Human
Reaction:     200 x 20 µl reactions desalted
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding primer assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCED0001031
Assay Design:   Exonic
Chromosome Location:   11:17464743-17464850question
Amplicon Length:   78
Splice Variants Targeted:   ENST00000389817 ENST00000302539 ENST00000379493

Gene Information

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1 MDR/TAP MRP ALD OABP GCN20 White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II an autosomal dominant disease of defective insulin secretion. Alternative splicing of this gene has been observed; however the transcript variants have not been fully described. [provided by RefSeq Jul 2008]

Gene Symbol:   ABCC8
Gene Name:   ATP-binding cassette, sub-family C (CFTR/MRP), member 8
Aliases:   ABC36, HHF1, HI, HRINS, MRP8, PHHI, SUR, SUR1, TNDM2
RefSeq:   NC_000011.9 NG_008867.1 NG_012446.1 NT_009237.18
Ensembl:   ENSG00000006071
Entrez:   6833
Chromosome Mapping:   11p15.1

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