PrimePCR™ Probe Assay: TAP1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: TAP1, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: TAP1, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0039851
Assay Design:   exonic
Chromosome Location:   6:32813316-32813461question
Amplicon Length:   116
Splice Variants Targeted:   ENST00000418205 ENST00000439781 ENST00000424897 ENST00000342213 ENST00000440894 ENST00000383235 ENST00000356406 ENST00000413009 ENST00000503233 ENST00000414467 ENST00000428324 ENST00000354258 ENST00000425148

Gene Information

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1 MDR/TAP MRP ALD OABP GCN20 White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble. Mutations in this gene may be associated with ankylosing spondylitis insulin-dependent diabetes mellitus and celiac disease. [provided by RefSeq Jul 2008]

Gene Symbol:   TAP1
Gene Name:   transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
Aliases:   ABC17, ABCB2, APT1, D6S114E, FLJ26666, FLJ41500, PSF1, RING4, TAP1*0102N, TAP1N
RefSeq:   NC_000006.11 NG_011759.1 NG_028165.1 NT_007592.15 NT_113891.2 NT_167244.1 NT_167245.1 NT_167246.1 NT_167247.1 NT_167248.1 NT_167249.1
Ensembl:   ENSG00000168394
Entrez:   6890
Chromosome Mapping:   6p21.3

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