PrimePCR™ Probe Assay: AKR7A2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0041619
Assay Design:   exonic
Chromosome Location:   1:19630484-19630627question
Amplicon Length:   114
Splice Variants Targeted:   ENST00000235835 ENST00000330072

Gene Information

The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein thought to be localized in the golgi catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde. [provided by RefSeq Oct 2011]

Gene Symbol:   AKR7A2
Gene Name:   aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
Aliases:   AFAR, AFAR1, AFB1-AR1, AKR7
RefSeq:   NC_000001.10 NT_004610.19
Ensembl:   ENSG00000053371
Entrez:   8574
Chromosome Mapping:   1p36.13

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