PrimePCR™ Probe Assay: EIF2B3, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: EIF2B3, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: EIF2B3, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0049562
Assay Design:   exonic
Chromosome Location:   1:45407215-45407336question
Amplicon Length:   92
Splice Variants Targeted:   ENST00000372182 ENST00000372183 ENST00000360403

Gene Information

The protein encoded by this gene is one of the subunits of initiation factor eIF2B which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Oct 2009]

Gene Symbol:   EIF2B3
Gene Name:   eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
Aliases:   EIF-2B, EIF2Bgamma
RefSeq:   NC_000001.10 NT_032977.9 NG_015864.1
Ensembl:   ENSG00000070785
Entrez:   8891
Chromosome Mapping:   1p34.1

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